An in vitro batch-culture model to estimate the effects of interventional regimens on human fecal microbiota

S Ahmadi, S Wang, R Nagpal, R Mainali… - JoVE (Journal of …, 2019 - jove.com
The emerging role of the gut microbiome in several human diseases demands a
breakthrough of new tools, techniques and technologies. Such improvements are needed to
decipher the utilization of microbiome modulators for human health benefits. However, the
large-scale screening and optimization of modulators to validate microbiome modulation
and predict related health benefits may be practically difficult due to the need for large
number of animals and/or human subjects. To this end, in vitro or ex vivo models can …